Nurse Betty is a 2000 American comedy film directed by Neil LaBute starring Renée Zellweger as a sweet Kansas waitress who undergoes a nervous breakdown after witnessing her husband's murder, and starts obsessively pursuing her favorite soap actor.
For her performance, Zellweger won the Golden Globe Award for Best Actress – Motion Picture Musical or Comedy.
Opening in a small Kansas town, Betty (Renée Zellweger), a kind and considerate diner waitress, is a fan of the soap opera, A Reason to Love. She has no idea that her husband, Del (Aaron Eckhart), a car salesman, is having an affair with his secretary and that he intends to leave Betty in order to pursue a relationship with the secretary. She also doesn't know that her husband supplements his income by selling drugs out of the car dealership.
When she calls to leave a message about borrowing a Buick LeSabre for her birthday, her husband tells Betty to take a different car as the LeSabre (unbeknownst to Betty) has stolen drugs...